?? ???? ????? ????? ??? ???????? ????? ??????? ????? ?? ??? ???? ?????? ?????? ????? ?????? ??????? ????? ????????? ????? ?????? ??? ????? ????? ???? ?? ???? ??? ??????? ??? ??????? ?? ??? ??????. Approvals of those medications are actually withdrawn since the medication are no longer shown being helpful and the benefits don't outweigh the hazar